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iolX [2019-05-22 13:51:17]
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iolX [2019-05-22 13:51:17]

scyllo-inositol 2-dehydrogenase
Locus
BSU10850
Isoelectric point
5.30
Molecular weight
37.33 kDa
Protein length
342 aa Sequence Blast
Gene length
1029 bp Sequence Blast
Function
utilization of scyllo-inositol
Product
scyllo-inositol 2-dehydrogenase
Essential
no
Synonyms
yuxD,yucG,yisS
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of inositol

    • Gene

    Coordinates
    1,164,370 1,165,398

    Phenotypes of a mutant

  • impaired growth with scyllo-inositol as the only carbon source PubMed

    • The protein

    Protein family

  • gfo/idh/mocA family (according to Swiss-Prot)

    • Paralogous protein(s)

  • YfiI, NtdC, YteT, IolU, IolG, YrbE, IolW

    • Cofactors

  • NAD+ PubMed

    • Structure

  • 3EZY (from Thermotoga maritima, 37% identity)

    • Expression and Regulation

    Operons

    Genes
    iolX
    Description
    PubMed

    Regulatory mechanism

  • IolQ: repression, PubMed, in IolQ regulon
    • Regulation
    induced by scyllo-inositol PubMed
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    Biological materials

    Mutant

  • MGNA-B191 (yisS::erm), available at the NBRP B. subtilis, Japan
  • BKE10850 (iolX::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACGTCCCATCCTCTCCTTT, downstream forward: _UP4_TAAAAGCTAAGTATGTTGCA
  • BKK10850 (iolX::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACGTCCCATCCTCTCCTTT, downstream forward: _UP4_TAAAAGCTAAGTATGTTGCA

    • References

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